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Article

Mutational analysis of CASP10 gene in colon, breast, lung and hepatocellular carcinomas.

Pathology - 1 Jan 2010

Oh Ji Eun, Kim Min Sung, Ahn Chang Hyeok, Kim Sung Soo, Han Ji Youn, Lee Sug Hyung, Yoo Nam Jin

Abstract excerpt

AIMS: Evasion of apoptosis is a feature of cancer cells. As a mechanism of apoptosis inactivation in cancer cells, somatic mutations of pro-apoptotic genes have been reported in many cancers. Caspase-10 is an initiation-phase caspase, and somatic mutation of CASP10 that encodes caspase-10 has been found in non-Hodgkin's lymphoma and gastric carcinoma. METHODS: The aim of this study was to explore whether CASP10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 20025484
DOI: 10.3109/00313020903434371

Genes

CASP10
CASP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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Inactivating mutations of caspase-8 gene in colorectal carcinomas.Semantic proximity Read ↗

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Association of CASP8 polymorphisms and cancer susceptibility: A meta-analysis.Semantic proximity Read ↗

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