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Article

Inhibition of apoptosis during development of colorectal cancer.

Cancer research - 1 May 1995

Bedi A, Pasricha P J, Akhtar A J, Barber J P, Bedi G C, Giardiello F M, Zehnbauer B A, Hamilton S R, Jones R J

Abstract excerpt

Colorectal tumorigenesis proceeds through an accumulation of specific genetic alterations. Studies of the mechanism by which these genetic changes effect malignant transformation have focused on the deregulation of cell proliferation. However, colorectal epithelial homeostasis is dependent not only on the rate of cell production but also on apoptosis, a genetically programmed process of autonomous cell death. We...

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Identifiers

PMID: 7728743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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