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Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Apr 2006

Soung Young Hwa, Lee Jong Woo, Kim Su Young, Park Won Sang, Nam Suk Woo, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

Mounting evidence indicates that deregulation of apoptosis is involved in the mechanisms of cancer development. Caspase-9 plays a crucial role in the initiation phase of the intrinsic apoptosis pathway. To explore the possibility that the genetic alterations of caspase-9 might be involved in the development of human cancers, we analyzed the entire coding region and all splice sites of the human caspase-9 gene for...

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Identifiers

PMID: 16689829
DOI: 10.1111/j.1600-0463.2006.apm_364.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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