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Article

MALT lymphoma and extranodal diffuse large B-cell lymphoma are targeted by aberrant somatic hypermutation.

Blood - 15 Apr 2007

Deutsch Alexander J A, Aigelsreiter Ariane, Staber Philipp B, Beham Alfred, Linkesch Werner, Guelly Christian, Brezinschek Ruth I, Fruhwirth Margareta, Emberger Werner, Buettner Maike, Beham-Schmid Christine, Neumeister Peter

Abstract excerpt

Recently, a novel mechanism introducing genetic instability, termed aberrant somatic hypermutation (ASHM), has been described in diffuse large B-cell lymphoma. To further investigate whether ASHM also occurs in mucosa-associated lymphoid tissue type (MALT) lymphoma, we studied the mutation profile of PIM1, PAX5, RhoH/TTF, and c-MYC in 17 MALT lymphomas and 17 extranodal diffuse large B-cell lymphomas (DLBCLs)...

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Share to PAX5 gene
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymphoma, B-Cell, Marginal Zone

Share to Lymphoma, Large B-Cell, Diffuse

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Share to Regulatory Sequences, Nucleic Acid

Source

Identifiers

PMID: 17197434
DOI: 10.1182/blood-2006-06-030494

Genes

MYC
PIM1
PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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