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Article

Aberrant somatic hypermutations in thyroid lymphomas.

Leukemia research - 1 May 2009

Takakuwa Tetsuya, Miyauchi Akira, Aozasa Katsuyuki

Abstract excerpt

To determine a possible role of aberrant somatic hypermutation (ASHM) in the pathogenesis of thyroid lymphoma (TL), mutational status of genes affected by ASHM, including c-MYC, PIM-1, PAX-5 and RhoH/TTF, was analyzed. Tumor specimens from 33 patients with thyroid B-cell lymphoma and 14 with chronic lymphocytic thyroiditis (CLTH), an autoimmune thyroiditis known to provide a basis for TL development, was...

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Source

Identifiers

PMID: 19019431
DOI: 10.1016/j.leukres.2008.10.007

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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