Article
Lack of Toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia.
Journal of Korean medical science - 1 Dec 2006
Yoon Hee Jung, Choi Jun Yong, Kim Chang Oh, Park Yoon Seon, Kim Myoung Soo, Kim Young Keun, Shin So Youn, Kim June Myung, Song Young Goo
Abstract excerpt
Toll-like receptors (TLRs) are pattern-recognition receptors that are important in innate immune responses to bacterial infection. The purpose of this study is to describe the prevalence of TLRs genetic variations in the bacteremic patients in Korea. A total of 154 patients with bacteremia and 179 healthy volunteers were included. The Asp299Gly and Thr399Ile allele of the TLR4 gene and Arg753Gln and Arg677Trp...
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