Article
Genetic polymorphisms of viral infection-associated Toll-like receptors in Chinese population.
Translational research : the journal of laboratory and clinical medicine - 1 Nov 2007
Cheng Pei-Lin, Eng Hock-Liew, Chou Ming-Huei, You Huey-Ling, Lin Tsun-Mei
Abstract excerpt
Toll-like receptors (TLRs) play a pivotal role in an innate immunity system, which controls inflammation responses and further instructs development of adaptive immunity. We enrolled 250 Han Chinese in Taiwan screening for the single nucleotide polymorphisms (SNPs) in TLRs associated with viral infection, including TLR2, TLR3, TLR4, TLR7, TLR8, and TLR9. The 6 SNPs not hitherto identified in Chinese populations,...
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