Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in toll-like receptor 4 in Mexican-Mestizo patients with intra-abdominal infection and/or pneumonia.

Immunology letters - 1 Jun 2013

Rodriguez-Osorio Carlos A, Lima Guadalupe, Herrera-Caceres Jaime O, Villegas-Torres Beatriz E, Zuñiga Joaquin, Ponce-de-Leon Sergio, Llorente Luis, Sifuentes-Osornio Jose

Abstract excerpt

Sepsis is a leading cause of death around the world, and 73-83% of all sepsis cases requiring attention in intensive care units are linked to intra-abdominal infection (IAI) or pneumonia. The activation of innate immunity is central to the manifestation of sepsis, and toll-like receptor (TLR) 4 plays an important role in this activation process. The 299G and 399I alleles of TLR4 have been linked with an increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungi
Share to Gram-Negative Bacteria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gram-Positive Bacteria

Share to Mexico

Share to Pneumonia

Share to Sepsis

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 23871732
DOI: 10.1016/j.imlet.2013.07.002

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in toll-like receptor 4 in Mexican-Mestizo patients with intra-abdominal infection and/or pneumonia.PMID 23871732Read ↗

Toll-like receptor 2, 4 and 9 polymorphisms and their association with ICU-acquired infections in Central Greece.Semantic proximity Read ↗

Effect of TLR-4 gene polymorphisms on sepsis susceptibility in neonates: a systematic review and meta-analysis.Semantic proximity Read ↗

Lack of association between TLR4 Asp299Gly and Thr399Ile polymorphisms and sepsis susceptibility: a meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease.Semantic proximity Read ↗

Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock.Semantic proximity Read ↗

Association between TLR4 A299G polymorphism and pneumonia risk: a meta-analysis.Semantic proximity Read ↗

Study of disease-relevant polymorphisms in the TLR4 and TLR9 genes: a novel method applied to the analysis of the Portuguese population.Semantic proximity Read ↗

The role of TLR4 896 A>G and 1196 C>T in susceptibility to infections: a review and meta-analysis of genetic association studies.Semantic proximity Read ↗

Association of TLR4 polymorphisms (Asp299Gly and Thr399Ile) with sepsis: a meta-analysis and trial sequence analysis.Semantic proximity Read ↗

Lack of Toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia.Semantic proximity Read ↗

Analysis of Toll-like Receptor 9 Gene Polymorphisms in Sepsis.Semantic proximity Read ↗

Toll-like receptor 4 polymorphisms in gram-negative bacterial infections of Han Chinese neonates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.