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Article

Frequency of TLR 2, 4, and 9 gene polymorphisms in Chinese population and their susceptibility to type 2 diabetes and coronary artery disease.

Journal of biomedicine & biotechnology - 1 Jan 2012

Liu Fengjing, Lu Weixin, Qian Qiaohui, Qi Weigang, Hu Jifan, Feng Bo

Abstract excerpt

Toll-like receptors (TLRs) are pivotal components of the innate immune response. Activation of the innate immune system and subsequent chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and type 2 diabetes. In the study, we genotyped TLRs gene polymorphisms, including TLR2 Arg677Trp and Arg753Gln, TLR4 Asp299Gly and Thr399Ile, TLR9-1486T/C and -1237T/C. The...

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Source

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Identifiers

PMID: 23091345
DOI: 10.1155/2012/373945
PMCID: PMC3469311

Genes

TLR9
TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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