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Article

The importance of Toll-like receptor 2 polymorphisms in severe infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Nov 2005

Texereau Joelle, Chiche Jean-Daniel, Taylor William, Choukroun Gerald, Comba Beatrice, Mira Jean-Paul

Abstract excerpt

Toll-like receptor 2 (TLR2) is a member of the TLR family, which plays a central role in the innate immune response to a wide variety of microorganisms. Animal studies have shown that TLR2-knockout mice are more susceptible to septicemia due to Staphylococcus aureus and Listeria monocytogenes, meningitis due to Streptococcus pneumoniae, and infection with Mycobacterium tuberculosis, suggesting that functional...

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Source

Identifiers

PMID: 16237639
DOI: 10.1086/431990

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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