Article
Very low frequencies of Toll-like receptor 2 supposed-2029T and 2258A (RS5743708) mutant alleles in southern Brazilian critically ill patients: would it be a lack of worldwide-accepted clinical applications of Toll-like receptor 2 variants?
Genetic testing and molecular biomarkers - 1 Jun 2010
Thurow Helena Strelow, Sarturi Cladinara Roberts, Fallavena Paulo Roberto Vargas, Paludo Francis Jackson de Oliveira, Picanço Juliane Bentes, Fraga Lucas Rosa, Graebin Pietra, de Souza Vinícius Carolino, Dias Fernando Suparregui, Nóbrega Otávio de Tolêdo, Alho Clarice Sampaio
Abstract excerpt
Toll-like receptor 2 (TLR2) is a recognition receptor for the widest repertoire of pathogen-associated molecular patterns. Two polymorphisms of TLR2 could be linked to reduced nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) activation and to increased risk of infection (sup...
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