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Article

DeltaF508 mutation results in impaired gastric acid secretion.

The Journal of biological chemistry - 2 Mar 2007

Sidani Shafik M, Kirchhoff Philipp, Socrates Thenral, Stelter Lars, Ferreira Elisa, Caputo Christina, Roberts Kurt E, Bell Robert L, Egan Marie E, Geibel John P

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) is recognized as a multifunctional protein that is involved in Cl(-) secretion, as well as acting as a regulatory protein. In order for acid secretion to take place a complex interaction of transport proteins and channels must occur at the apical pole of the parietal cell. Included in this process is at least one K(+) and Cl(-) channel, allowing for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17178714
DOI: 10.1074/jbc.M608427200

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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