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Article

Acid-stimulated duodenal bicarbonate secretion involves a CFTR-mediated transport pathway in mice.

Gastroenterology - 1 Aug 1997

Hogan D L, Crombie D L, Isenberg J I, Svendsen P, Schaffalitzky de Muckadell O B, Ainsworth M A

Abstract excerpt

BACKGROUND & AIMS: Duodenal bicarbonate secretion is an important factor in epithelial protection. The role of the cystic fibrosis transmembrane conductance regulator (CFTR) in acid-induced bicarbonate secretion is unknown. The aim of this study was to determine whether CFTR mediates acid-stimulated duodenal epithelial bicarbonate secretion. METHODS: Basal and stimulated bicarbonate secretion was examined in the...

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Source

Identifiers

PMID: 9247473
DOI: 10.1053/gast.1997.v113.pm9247473

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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