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Article

Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy.

Circulation - 2 Sept 2003

Schmitt Joachim P, Semsarian Christopher, Arad Michael, Gannon Joseph, Ahmad Ferhaan, Duffy Catherine, Lee Richard T, Seidman Christine E, Seidman J G

Abstract excerpt

BACKGROUND: Whether ventricular remodeling from hypertrophic cardiomyopathy (HCM), systemic hypertension, or other pathologies arises through a common signaling pathway or through independent molecular mechanisms is unknown. To study this, we assessed cardiac hypertrophy in a mouse model of HCM subjected to increased left ventricular (LV) load. METHODS AND RESULTS: Transverse aortic banding of mice with or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12925456
DOI: 10.1161/01.CIR.0000086469.85750.48

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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