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Article

Variable phenotype in murine transverse aortic constriction.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000

Mohammed Selma F, Storlie Jimmy R, Oehler Elise A, Bowen Lorna A, Korinek Josef, Lam Carolyn S P, Simari Robert D, Burnett John C, Redfield Margaret M

Abstract excerpt

BACKGROUND: In mice, transverse aortic constriction (TAC) is variably characterized as a model of pressure overload-induced hypertrophy (left ventricular [LV] hypertrophy, or LVH) or heart failure (HF). While commonly used, variability in the TAC model is poorly defined. The objectives of this study were to characterize the variability in the TAC model and to define a simple, noninvasive method of prospectively...

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Share to Constriction, Pathologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypertrophy, Left Ventricular

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Share to Ventricular Dysfunction, Left

Source

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Identifiers

PMID: 21764606
DOI: 10.1016/j.carpath.2011.05.002
PMCID: PMC3412352

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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