Article
Antibody induction of lupus-like neuropsychiatric manifestations.
Journal of neuroimmunology - 1 Jan 2007
Lawrence David A, Bolivar Valerie J, Hudson Chad A, Mondal Tapan K, Pabello Nina G
Abstract excerpt
Although systemic lupus erythematosus (SLE) is usually evaluated with regard to autoimmune reactivity toward the kidney, there are multiple psychiatric abnormalities associated with this autoimmune disease. Lupus-prone male NZM88 mice, derived from NZB/NZW F1 mice, develop early neuropsychiatric manifestations without any signs of nephritis. In addition to the usual repertoire of antibody specificities, including...
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