Article
Neuropsychiatric SLE: from animal model to human.
Lupus - 1 Apr 2017
Pikman R, Kivity S, Levy Y, Arango M-T, Chapman J, Yonath H, Shoenfeld Y, Gofrit S G
Abstract excerpt
Animal models are a key element in disease research and treatment. In the field of neuropsychiatric lupus research, inbred, transgenic and disease-induced mice provide an opportunity to study the pathogenic routes of this multifactorial illness. In addition to achieving a better understanding of the immune mechanisms underlying the disease onset, supplementary metabolic and endocrine influences have been...
Read the complete abstract on PubMedTopics
- Animals
- Animals, Genetically Modified
- Autoantibodies
- Cytokines
- Disease Models, Animal
- Genetic Predisposition to Disease
- Humans