Article
Chronic Presence of Blood Circulating Anti-NMDAR1 Autoantibodies Impairs Cognitive Function in Mice
2021-04-22
Abstract excerpt
High titers of anti-NMDAR1 autoantibodies in brain cause anti-NMDAR1 encephalitis that displays psychiatric symptoms of schizophrenia and/or other psychiatric disorders in addition to neurological symptoms. Low titers of anti-NMDAR1 autoantibodies are reported in the blood of a subset of the general human population and psychiatric patients. Since ∼0.1-0.2% of blood circulating antibodies cross the blood-brain bar...
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Identifiers and source
- Literature Corpus work
- be7bcaf6-7fe1-50e9-84c6-7bb6edeb243f
- DOI
- 10.1101/2021.04.22.440976
