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Article

Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background.

Frontiers in immunology - 1 Jan 2024

Li Yaxi, Zhang Shu, Tang Chenling, Yang Bowen, Atrooz Fatin, Ren Zhifeng, Mohan Chandra, Salim Samina, Wu Tianfu

Abstract excerpt

Introduction: Systemic Lupus Erythematosus (SLE) impacts the central nervous system (CNS), leading to severe neurological and psychiatric manifestations known as neuropsychiatric lupus (NPSLE). The complexity and heterogeneity of clinical presentations of NPSLE impede direct investigation of disease etiology in patients. The limitations of existing mouse models developed for NPSLE obstruct a comprehensive...

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Identifiers

PMID: 38524134
DOI: 10.3389/fimmu.2024.1370254
PMCID: PMC10960363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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