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Article

Inferring the distribution of mutational effects on fitness in Drosophila.

Biology letters - 22 Sept 2006

Loewe Laurence, Charlesworth Brian

Abstract excerpt

The properties of the distribution of deleterious mutational effects on fitness (DDME) are of fundamental importance for evolutionary genetics. Since it is extremely difficult to determine the nature of this distribution, several methods using various assumptions about the DDME have been developed, for the purpose of parameter estimation. We apply a newly developed method to DNA sequence polymorphism data from...

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Identifiers

PMID: 17148422
DOI: 10.1098/rsbl.2006.0481
PMCID: PMC1686194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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