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Article

Causes of natural variation in fitness: evidence from studies of Drosophila populations.

Proceedings of the National Academy of Sciences of the United States of America - 10 Feb 2015

Charlesworth Brian

Abstract excerpt

DNA sequencing has revealed high levels of variability within most species. Statistical methods based on population genetics theory have been applied to the resulting data and suggest that most mutations affecting functionally important sequences are deleterious but subject to very weak selection. Quantitative genetic studies have provided information on the extent of genetic variation within populations in...

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Identifiers

PMID: 25572964
DOI: 10.1073/pnas.1423275112
PMCID: PMC4330759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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