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Article

Estimation of deleterious genomic mutation parameters in natural populations by accounting for variable mutation effects across loci.

Genetics - 1 Nov 2002

Deng Hong-Wen, Gao Guimin, Li Jin-Long

Abstract excerpt

The genomes of all organisms are subject to continuous bombardment of deleterious genomic mutations (DGM). Our ability to accurately estimate various parameters of DGM has profound significance in population and evolutionary genetics. The Deng-Lynch method can estimate the parameters of DGM in natural selfing and outcrossing populations. This method assumes constant fitness effects of DGM and hence is biased...

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Identifiers

PMID: 12454090
DOI: 10.1093/genetics/162.3.1487
PMCID: PMC1462319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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