Article

Inferring genome-wide correlations of mutation fitness effects between populations

2019-07-16

Abstract excerpt

The effect of a mutation on fitness may differ between populations depending on environmental and genetic context, but little is known about the factors that underlie such differences. To quantify genome-wide correlations in mutation fitness effects, we developed a novel concept called a joint distribution of fitness effects (DFE) between populations. We then proposed a new statistic w to measure the DFE correlat...

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Literature Corpus work: bf348154-01a6-5ebb-9c6c-a8b9ed4b444f
DOI: 10.1101/703918

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