Article

Quantifying the fraction of new mutations that are recessive lethal

2022-04-22

Abstract excerpt

The presence and impact of recessive lethal mutations has been widely documented in diploid outcrossing species. However, precise estimates in different species of the proportion of mutations that are recessive lethal remain limited. Here, we attempt to quantify the fraction of new mutations that are recessive lethal using Fit ∂ a ∂ i, a commonly-used method for inferring the distribution of fitness effects (DFE...

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Literature Corpus work: bb4a588b-11ee-5fe7-94b9-b85a7cee3911
DOI: 10.1101/2022.04.22.489225

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