Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced folate supply as a key to enhanced L-serine production by Corynebacterium glutamicum.

Applied and environmental microbiology - 1 Feb 2007

Stolz Michael, Peters-Wendisch Petra, Etterich Helga, Gerharz Tanja, Faurie Robert, Sahm Hermann, Fersterra Holger, Eggeling Lothar

Abstract excerpt

The amino acid L-serine is required for pharmaceutical purposes, and the availability of a sugar-based microbial process for its production is desirable. However, a number of intracellular utilization routes prevent overproduction of L-serine, with the essential serine hydroxymethyltransferase (SHMT) (glyA) probably occupying a key position. We found that constructs of Corynebacterium glutamicum strains where...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Serine
Share to Biotechnology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Corynebacterium glutamicum

Share to Culture Media

Share to Folic Acid

Share to Genetic Engineering

Share to Glycine Hydroxymethyltransferase

Share to Tetrahydrofolates

Source

Open in PubMed Open full text

Identifiers

PMID: 17142381
DOI: 10.1128/AEM.02208-06
PMCID: PMC1800755

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced folate supply as a key to enhanced L-serine production by Corynebacterium glutamicum.PMID 17142381Read ↗

Engineering of high yield production of L-serine in Escherichia coli.Semantic proximity Read ↗

A novel aceE mutation leading to a better growth profile and a higher L-serine production in a high-yield L-serine-producing Corynebacterium glutamicum strain.Semantic proximity Read ↗

Progress in the microbial production of S-adenosyl-L-methionine.Semantic proximity Read ↗

Characteristics of methionine production by an engineered Corynebacterium glutamicum strain.Semantic proximity Read ↗

Analysis of α-isopropylmalate synthase variant and its effect on L-leucine synthesis in Corynebacterium glutamicumSemantic proximity Read ↗

Moonlighting glutamate formiminotransferases can functionally replace 5-formyltetrahydrofolate cycloligase.Semantic proximity Read ↗

A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production.Semantic proximity Read ↗

A novel methodology employing Corynebacterium glutamicum genome information to generate a new L-lysine-producing mutant.Semantic proximity Read ↗

A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum.Semantic proximity Read ↗

Cysteine biosynthesis in Lactobacillus casei: identification and characterization of a serine acetyltransferase.Semantic proximity Read ↗

Heterologous Production of the D-Cycloserine Intermediate O-acetyl-L-serine in Human Lung Cancer CellsSemantic proximity Read ↗

Disruption of genes for the enhanced biosynthesis of α-ketoglutarate in Corynebacterium glutamicum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.