Article
A novel gnd mutation leading to increased L-lysine production in Corynebacterium glutamicum.
FEMS microbiology letters - 15 Jan 2005
Ohnishi Junko, Katahira Ritsuko, Mitsuhashi Satoshi, Kakita Shingo, Ikeda Masato
Abstract excerpt
Toward more efficient L-lysine production, we have been challenging genome-based strain breeding by the approach of assembling only relevant mutations in a single wild-type background. Following the creation of a new L-lysine producer Corynebacterium glutamicum AHP-3 that carried three useful mutations (lysC311, hom59, and pyc458) on the relevant downstream pathways, we shifted our target to the pentose phosphate...
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