Article

Analysis of α-isopropylmalate synthase variant and its effect on L-leucine synthesis in Corynebacterium glutamicum

2022-07-08

Abstract excerpt

<h4>Purpose: </h4> L-Leucine is an essential amino acid for humans since it is only synthesized in fungi, bacteria, and plants. Its production has not been well documented as L-lysine and L-glutamic acid due to multivalent regulation and longer synthesis pathways. In Corynebacterium glutamicum , L-leucine synthesis is strongly regulated at α-isopropylmalate synthase (α-IMPS) node by the end product. Amino acid sub...

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Literature Corpus work: 03eb0347-229c-53d6-ab04-f4aff3d03bad
DOI: 10.21203/rs.3.rs-1717587/v1

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