Article
Characteristics of methionine production by an engineered Corynebacterium glutamicum strain.
Metabolic engineering - 1 Jul 2007
Park Soo-Dong, Lee Joo-Young, Sim Soo-Yeon, Kim Younhee, Lee Heung-Shick
Abstract excerpt
A methionine-producing strain was derived from a lysine-producing Corynebacterium glutamicum through a process of genetic manipulation in order to assess its potential to synthesize and accumulate methionine during growth. The strain carries a deregulated hom gene (hom(FBR)) to abolish feedback inhibition of homoserine dehydrogenase by threonine and a deletion of the thrB gene (delta thrB) to abolish threonine...
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