Article
A novel aceE mutation leading to a better growth profile and a higher L-serine production in a high-yield L-serine-producing Corynebacterium glutamicum strain.
Journal of industrial microbiology & biotechnology - 1 Sept 2016
Guo Wen, Chen Ziwei, Zhang Xiaomei, Xu Guoqiang, Zhang Xiaojuan, Shi Jinsong, Xu Zhenghong
Abstract excerpt
A comparative genomic analysis was performed to study the genetic variations between the L-serine-producing strain Corynebacterium glutamicum SYPS-062 and the mutant strain SYPS-062-33a, which was derived from SYPS-062 by random mutagenesis with enhanced L-serine production. Some variant genes between the two strains were reversely mutated or deleted in the genome of SYPS-062-33a to verify the influences of the...
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