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Article

Evaluation of six methods for estimating synonymous and nonsynonymous substitution rates.

Genomics, proteomics & bioinformatics - 1 Aug 2006

Zhang Zhang, Yu Jun

Abstract excerpt

Methods for estimating synonymous and nonsynonymous substitution rates among protein-coding sequences adopt different mutation (substitution) models with subtle yet significant differences, which lead to different estimates of evolutionary information. Little attention has been devoted to the comparison of methods for obtaining reliable estimates since the amount of sequence variations within targeted datasets is...

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Identifiers

PMID: 17127215
DOI: 10.1016/S1672-0229(06)60030-2
PMCID: PMC5054070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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