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Article

Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site.

Molecular biology and evolution - 1 Jul 1994

Ota T, Nei M

Abstract excerpt

Nei and Gojobori (1986) developed a simple method to estimate the numbers of synonymous (ds) and nonsynonymous (dN) substitutions per site. In the present paper, we have developed a method for computing variances and covariances of ds's and dN's and of the proportions of synonymous (ps) and nonsynonymous (pN) differences. We also have developed a method for computing the variances of mean dS, dN, pS, pN, without...

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PMID: 8078400
DOI: 10.1093/oxfordjournals.molbev.a040140

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