Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site.

doi:10.1093/oxfordjournals.molbev.a040140

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Article

Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site.

Molecular biology and evolution - 1 Jul 1994

Ota T, Nei M

Abstract excerpt

Nei and Gojobori (1986) developed a simple method to estimate the numbers of synonymous (ds) and nonsynonymous (dN) substitutions per site. In the present paper, we have developed a method for computing variances and covariances of ds's and dN's and of the proportions of synonymous (ps) and nonsy...

Topics

Computer Simulation
Models, Genetic
Mutation
Selection, Genetic

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