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Article

Variation in the pattern of nucleotide substitution across sites.

Journal of molecular evolution - 1 Jan 1999

Huelsenbeck J P, Nielsen R

Abstract excerpt

A model of nucleotide substitution that allows the transition/transversion rate bias to vary across sites was constructed. We examined the fit of this model using likelihood-ratio tests by analyzing 13 protein coding genes and 1 pseudogene. Likelihood-ratio testing indicated that a model that allows variation in the transition/transversion rate bias across sites provided a significant improvement in fit for most...

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PMID: 9873080
DOI: 10.1007/pl00006448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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