New methods for estimating the numbers of synonymous and nonsynonymous substitutions.

doi:10.1007/BF00167113

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Article

New methods for estimating the numbers of synonymous and nonsynonymous substitutions.

Journal of molecular evolution - 1 Feb 1995

Ina Y

Abstract excerpt

New methods for estimating the numbers of synonymous and nonsynonymous substitutions per site were developed. The methods are unweighted pathway methods based on Kimura's two-parameter model. Computer simulations were conducted to evaluate the accuracies of the new methods, Nei and Gojobori's (NG...

Topics

Animals
Computer Simulation
Humans
Models, Genetic
Mutation

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