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Article

The relationship between dN/dS and scaled selection coefficients.

Molecular biology and evolution - 1 Apr 2015

Spielman Stephanie J, Wilke Claus O

Abstract excerpt

Numerous computational methods exist to assess the mode and strength of natural selection in protein-coding sequences, yet how distinct methods relate to one another remains largely unknown. Here, we elucidate the relationship between two widely used phylogenetic modeling frameworks: dN/dS models and mutation-selection (MutSel) models. We derive a mathematical relationship between dN/dS and scaled selection...

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Identifiers

PMID: 25576365
DOI: 10.1093/molbev/msv003
PMCID: PMC4379412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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