Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of schizotypy on cognitive performance and its tuning by COMT val158 met genotype variations in a large population of young men.

Biological psychiatry - 1 Apr 2007

Smyrnis Nikolaos, Avramopoulos Dimitrios, Evdokimidis Ioannis, Stefanis Costas N, Tsekou Hara, Stefanis Nicholas C

Abstract excerpt

BACKGROUND: Mirroring schizophrenia, specific dimensions of schizotypy are related to cognitive dysfunction. The relation of schizotypy and state psychopathology to cognitive performance and its link to catechol-O-methyltransferase (COMT) val(158) met genotype variations was studied in a large sample of young men. METHODS: State psychopathology and schizotypy were assessed with self-rated questionnaires....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methionine

Share to Personality Tests

Share to Psychometrics

Share to Psychomotor Performance

Share to Schizotypal Personality Disorder

Share to Valine

Source

Identifiers

PMID: 17123481
DOI: 10.1016/j.biopsych.2006.07.019

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of schizotypy on cognitive performance and its tuning by COMT val158 met genotype variations in a large population of young men.PMID 17123481Read ↗

Variation in catechol-o-methyltransferase val158 met genotype associated with schizotypy but not cognition: a population study in 543 young men.Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groups.Semantic proximity Read ↗

Effects of COMT genotype on cognitive ability and functional capacity in individuals with schizophrenia.Semantic proximity Read ↗

Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia.Semantic proximity Read ↗

Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia.Semantic proximity Read ↗

COMT-by-sex interaction effect on psychosis proneness.Semantic proximity Read ↗

Schizotypal dimensions: an intermediate phenotype associated with the COMT high activity allele.Semantic proximity Read ↗

Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls.Semantic proximity Read ↗

Interrogating the Relationship Between Schizotypy, the Catechol-O-Methyltransferase (COMT) Val158Met Polymorphism, and Neuronal Oscillatory Activity.Semantic proximity Read ↗

Catechol-O-methyltransferase genotype differentially contributes to the flexibility and stability of cognitive sets in patients with psychotic disorders and their first-degree relatives.Semantic proximity Read ↗

COMT Val 158 Met polymorphism is associated with cognitive flexibility in a signal discrimination task in schizophrenia.Semantic proximity Read ↗

COMT, neuropsychological function and brain structure in schizophrenia: a systematic review and neurobiological interpretation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.