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Article

Lectin-resistant CHO glycosylation mutants.

Methods in enzymology - 1 Jan 2006

Patnaik Santosh Kumar, Stanley Pamela

Abstract excerpt

Chinese hamster ovary (CHO) mutant cells with a wide variety of alterations in the glycosylation of proteins and lipids have been isolated by selection for resistance to the cytotoxicity of plant lectins. These CHO mutants have been used to characterize glycosylation pathways, to identify genes that code for glycosylation activities, to elucidate functional roles of glycans that mediate biological processes, and...

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PMID: 17113866
DOI: 10.1016/S0076-6879(06)16011-5

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