Glycosyltransferase mutants: key to new insights in glycobiology.

Abstract excerpt

Glycosyltransferases (Glyc-T's) catalyze the synthesis of the carbohydrate portions of glycoproteins, glycolipids, and proteoglycans. Most Glyc-T's transfer one sugar in one linkage and are encoded by a unique gene. Thus, synthesis of a branched carbohydrate may require expression of at least 30 Glyc-T genes. Mutations that alter Glyc-T activity therefore provide an approach to identifying functions for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Structure-Activity Relationship
• Share to Carbohydrate Sequence