A subclass of cell surface carbohydrates revealed by a CHO mutant with two glycosylation mutations.

doi:10.1093/glycob/1.3.307

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Article

A subclass of cell surface carbohydrates revealed by a CHO mutant with two glycosylation mutations.

Glycobiology - 1 Jun 1991

Stanley P, Sundaram S, Sallustio S

Abstract excerpt

A novel lectin-resistance phenotype was displayed by a LEC10 Chinese hamster ovary (CHO) cell mutant that was selected for resistance to the erythroagglutinin, E-PHA. Biochemical and genetic analyses revealed that the phenotype results from the expression of two glycosylation mutations, LEC10 and lec8. The LEC10 mutation causes the appearance of N-acetylglucosaminyltransferase III (GlcNAc-TIII) activity and the...

Topics

Animals
CHO Cells
Carbohydrate Conformation
Carbohydrate Sequence
Carbon Radioisotopes
Chromatography, Affinity
Cricetinae
Galactose
Genetic Complementation Test
Glucose
Glucosyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glycopeptides

Glycoproteins

Glycosylation

Golgi Apparatus

Magnetic Resonance Spectroscopy

Molecular Sequence Data

Mutation

Source

Open in PubMed

Identifiers

PMID: 1838951
DOI: 10.1093/glycob/1.3.307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1838951-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A subclass of cell surface carbohydrates revealed by a CHO mutant with two glycosylation mutations.PMID 1838951Read ↗

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