Article
Juxtaposed Polycomb complexes co-regulate vertebral identity.
Development (Cambridge, England) - 1 Dec 2006
Kim Se Young, Paylor Suzanne W, Magnuson Terry, Schumacher Armin
Abstract excerpt
Best known as epigenetic repressors of developmental Hox gene transcription, Polycomb complexes alter chromatin structure by means of post-translational modification of histone tails. Depending on the cellular context, Polycomb complexes of diverse composition and function exhibit cooperative interaction or hierarchical interdependency at target loci. The present study interrogated the genetic, biochemical and...
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