Article
Epigenetic balance of gene expression by Polycomb and COMPASS families.
Science (New York, N.Y.) - 3 Jun 2016
Piunti Andrea, Shilatifard Ali
Abstract excerpt
Epigenetic regulation of gene expression in metazoans is central for establishing cellular diversity, and its deregulation can result in pathological conditions. Although transcription factors are essential for implementing gene expression programs, they do not function in isolation and require the recruitment of various chromatin-modifying and -remodeling machineries. A classic example of developmental chromatin...
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