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Article

The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2002

Wang Jianbo, Mager Jesse, Schnedier Elizabeth, Magnuson Terry

Abstract excerpt

The Polycomb group (PcG) of genes was first identified in Drosophila as maintenance factors for long-term transcriptional repression of homeotic genes. In mice, the PcG protein Eed (Embryonic ectoderm development) is present in a distinct complex that interacts with histone deacetylase (HDAC) and the PcG member Ezh2 (Enhancer of zeste homolog 2), but not in the larger Polycomb repressive complex 1 (PRC1) formed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12370779
DOI: 10.1007/s00335-002-2182-7

Genes

PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.PMID 12370779Read ↗

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<i>Eed</i> controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crestSemantic proximity Read ↗

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Loss of Polycomb Repressive Complex 2 Function Alters Digestive Organ Homeostasis and Neuronal Differentiation in Zebrafish.Semantic proximity Read ↗

Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.Semantic proximity Read ↗

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Genome imprinting regulated by the mouse Polycomb group protein Eed.Semantic proximity Read ↗

The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo.Semantic proximity Read ↗

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