Article
Mitochondrial DNA mutations and 8-hydroxy-2'-deoxyguanosine Content in Japanese patients with urinary bladder and renal cancers.
Anticancer research - 1 Jan 2000
Wada Takashi, Tanji Nozomu, Ozawa Akira, Wang Jianbo, Shimamoto Kenji, Sakayama Kenshi, Yokoyama Masayoshi
Abstract excerpt
BACKGROUND: Several recent studies have demonstrated the presence of mitochondrial DNA (mtDNA) mutations in various human cancers. The origin of these mutations may be attributable to oxidative damage from reactive oxygen species (ROS). In order to investigate the relationship between mtDNA mutat...
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