Article
Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients.
International journal of cancer - 1 Jul 2012
Dasgupta Santanu, Shao Chunbo, Keane Thomas E, Duberow David P, Mathies Richard A, Fisher Paul B, Kiemeney Lambertus A, Sidransky David
Abstract excerpt
Our study aims at understanding the timing and nature of mitochondrial deoxyribonucleic acid (mtDNA) alterations in urothelial cell carcinoma (UCC) and their detection in urine sediments. The entire 16.5 kb mitochondrial genome was sequenced in matched normal lymphocytes, tumor and urine sediment...
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