Article
[Analysis of mitochondrial DNA D-loop region mutation and its significance in human oncocytoma].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Oct 2010
Song Wen-jing, Yan Li-min, Zhao Xiu-lan, Liu Zeng-hui, Sun Bao-cun
Abstract excerpt
OBJECTIVE: To investigate the mutation in mitochondrial DNA displacement-loop (mtDNA D-loop) region in oncocytoma and its relationship with tumorigenesis and tumor development. METHODS: The mtDNA D-Loop region of 20 thyroid or renal oncocytomas and the adjacent normal tissues were amplified by PCR, and then sequenced. Five human fetal renal tissues were collected as matched controls. RESULTS: Among the 20...
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