Article
Mitochondrial DNA mutations in chemical carcinogen-induced rat bladder and human bladder cancer.
Oncology reports - 1 Aug 2004
Chen Guang Fu, Chan Franky L, Hong Bao Fa, Chan L W, Chan Peter S F
Abstract excerpt
Mitochondrial (mt) DNA mutations have been described recently in different tumors, whereas similar studies focusing on bladder cancer are scarce. In an effort to understand the significance of mtDNA mutations in bladder cancer, we investigated the mtDNA alterations in both clinical human bladder cancer and in a carcinogen-induced rat bladder cancer model. Human bladder cancer tissues were obtained by radical...
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