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Article

Mutations of mtDNA in renal cell tumours arising in end-stage renal disease.

The Journal of pathology - 1 Feb 2003

Nagy Anetta, Wilhelm Monica, Kovacs Gyula

Abstract excerpt

Toxic effects in the uraemic state or during maintenance dialysis have been suggested to be responsible for DNA damage and tumour development in end-stage renal disease (ESRD). This study therefore analysed the mitochondrial DNA alterations in six kidneys with ESRD and in nine renal cell tumours arising in these kidneys. Sequencing the entire 16 569 bp mitochondrial genome disclosed 94 sequence variations in...

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Share to Carcinoma, Renal Cell
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Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Diseases, Cystic

Share to Kidney Failure, Chronic

Share to Kidney Neoplasms

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Source

Identifiers

PMID: 12533837
DOI: 10.1002/path.1273

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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