Article
Lack of association between mutations of gene-encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan.
Journal of negative results in biomedicine - 5 Nov 2009
Chen Jin-Bor, Lin Tsu-Kung, Liao Shang-Chih, Lee Wen-Chin, Lee Lung-Chih, Liou Chia-Wei, Wang Pei-Wen, Tiao Mao-Meng
Abstract excerpt
BACKGROUND: Mitochondria (mt) are highly susceptible to reactive oxygen species (ROS). In this study, we investigated the association between a region within the displacement loop (D-loop) in mtDNA that is highly susceptible to ROS and oxidative stress markers in chronic dialysis patients. We enrolled 184 chronic dialysis patients and 213 age-matched healthy subjects for comparison. Blood levels of oxidative...
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