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Article

The v-src oncogene blocks the differentiation of a murine myeloid progenitor cell line and induces a tumorigenic phenotype.

Oncogene - 1 Feb 1991

Krüger A, Anderson S M

Abstract excerpt

We have investigated the ability of the v-src oncogene to block the differentiation of the murine myeloid progenitor cell line 32D cl3. In response to granulocyte-colony stimulating factor (G-CSF), 32D cl3 cells are induced to differentiate into mature granulocytes (Valtieri et al., 1987). In con...

Topics

Animals
Cell Differentiation
Cell Transformation, Neoplastic
Gene Expression
Genes, src
Granulocyte Colony-Stimulating Factor
Hematopoietic Stem Cells
Lactoferrin
Mice
Neoplasm Transplantation
Neoplasms, Experimental
Peroxidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Proto-Oncogene Proteins pp60(c-src)

RNA, Messenger

Tumor Cells, Cultured

Source

Identifiers

PMID: 1705687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1705687-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The v-src oncogene blocks the differentiation of a murine myeloid progenitor cell line and induces a tumorigenic phenotype.PMID 1705687Read ↗

The v-src oncogene may not be responsible for the increased radioresistance of hematopoietic progenitor cells expressing v-src.Semantic proximity Read ↗

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