Article
Functions of the v-Src protein tyrosine kinase.
Cell biology international - 1 May 1994
Fincham V, Frame M, Haefner B, Unlu M, Wyke A, Wyke J
Abstract excerpt
The peripheral non-receptor tyrosine kinase oncoprotein, v-Src, has pleiotropic effects. It is a mitogen for quiescent cells, substituting for both competence and progression factor-mediated signals but it also induces cellular morphological transformation. We are dissecting the activities of v-S...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- Cells, Cultured
- Enzyme Activation
- Mitogen-Activated Protein Kinase 1
- Mitosis
- Models, Biological
- Mutation
- Oncogene Protein pp60(v-src)
- Protein Serine-Threonine Kinases
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins c-jun