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Article

Differentiation induced by the c-Mpl cytokine receptor is blocked by mutant Shc adaptor protein.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Sept 1996

Hill R J, Zozulya S, Lu Y L, Hollenbach P W, Joyce-Shaikh B, Bogenberger J, Gishizky M L

Abstract excerpt

c-Mpl, a member of the cytokine receptor superfamily, induces both proliferative and differentiation responses when stimulated with its ligand thrombopoietin (TPO). To examine signal transduction pathways associated with differentiation versus proliferation, 32D clone 3 cells, a murine interleukin 3-(IL-3)-dependent cell line capable of granulocytic differentiation, were engineered to express human c-Mpl...

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Identifiers

PMID: 8877093

Genes

TPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differentiation induced by the c-Mpl cytokine receptor is blocked by mutant Shc adaptor protein.PMID 8877093Read ↗

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